Monthly Healthcare Review July 2016 - BioEnterprise

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Monthly Healthcare Review July 2016 IPOs The following table includes the medical devices, biotechnology, pharmaceuticals, and healthcare IPO pricings, filings and withdrawals announced over the previous month.

Company Name

Last Financing Date

HQ Location

Description

Last Financing Size (Millions)

Kadmon Corporation (KDMN)

27-Jul-16

New York, NY Developer of biopharmaceutical products for the treatment and management of hepatitis C. 75.00

Patheon

21-Jul-16

Durham, NC

Provider of pharmaceutical development and manufacturing services from early development through late development to commercial manufacturing, including life cycle management services.

625.00

Audentes Therapeutics 20-Jul-16 (BOLD)

San Francisco, Operator of a biotechnology company focused on gene therapy treatments for serious rare CA diseases. The company develops new treatments through the application of adenoassociated virus (AAV) gene-therapy technology.

75.00

GenSight Biologics

Paris, France

44.96

13-Jul-16

Compiled by: Morgan Reape Source: Pitchbook

Developer of ophthalmic therapeutic devices for retinal degeneration. The company develops a gene replacement therapy for lebers hereditary optic neuropathy and an optogenetic therapy for retinitis pigmentosa.

Lead Manager

JMP Securities J.P. Morgan, Morgan Stanley, Jefferies, UBS Investment Bank, Credit Suisse, Evercore ISI, Wells Fargo Securities BofA Merrill Lynch, Cowen & Company, Piper Jaffray Canaccord Genuity, Evercore Group, Leerink Partners

1

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

HQ Location

Round

Description

VytronUS

29-Jul-16

Sunnyvale, CA

Later Stage VC Manufacturer of a device that uses both imaging capabilities and ultrasound energy to treat cardiac arrhythmia.

Timeless Herbal Care

29-Jul-16

Kingston, Jamaica

Angel

nVision Medical

28-Jul-16

Modulated Imaging

Financing Size (Millions)

49.00

Apple Tree Partners, New Enterprise Associates, BioStar Ventures

Producer of medical marijuana, herbal beverages, spa therapy rubs and 0.63 vaporizers. Mountain View, CA Later Stage VC Developer of a medical device to detect ovarian cancer and tube blockage. 12.00 Its focus is on advancing the diagnosis and treatment of female infertility caused by fallopian tube dysfunction by leveraging and adapting state of the art technologies from other medical disciplines.

Undisclosed

28-Jul-16

Irvine, CA

Seed Round

Developer of light-based methods for medical diagnostics. The company engages in focusing on wound care screening and techniques for noninvasive diagnostic and therapy monitoring applications.

The Cove Fund

ECG for Everybody

28-Jul-16

Novi Sad, Serbia

Accelerator/ Incubator

Developer of mobile devices, software for ECG sensing and a telemedical 0.02 platform for monitoring and recording of health parameters.

Avails Medical

28-Jul-16

Menlo Park, CA

Early Stage VC Developer and provider of non-invasive therapeutic drug monitoring devices to determine optimum drug dosage in epileptic patients.

Phosphorus

27-Jul-16

New York, NY

Early Stage VC Developer of data-driven software that delivers clinical tests to decode the 10.00 genetic causes of infertility. The company is building a genomic data network that will allow providers, researchers and patients to understand and harness the power of the human genome that causes infertility.

FirstMark Capital

Flower Orthopedics

27-Jul-16

Horsham, PA

Later Stage VC Developer of medical devices and implants for orthopedic surgery. The company develops sterile procedure-based medical tools for orthopedic surgeries and bone-fixation.

Undisclosed

Compiled by: Morgan Reape Source: Pitchbook

0.50

0.55

2.35

Arboretum Ventures

Startupbootcamp

The Explore Group, other undisclosed

2

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

HQ Location

Biodesix

27-Jul-16

Boulder, CO

Big Health

27-Jul-16

London, United Kingdom

Aushon BioSystems

27-Jul-16

Billerica, MA

AgeneBio

27-Jul-16

Baltimore, MD

3Derm Systems

27-Jul-16

Boston, MA

PowerVision

26-Jul-16

Belmont, CA

Omniox

26-Jul-16

San Carlos, CA

Compiled by: Morgan Reape Source: Pitchbook

Round

Description

Financing Size (Millions)

Later Stage VC Developer of blood-based tests. The company provides VeriStrat, a pretreatment serum testing tool that helps oncologists select treatments between erlotinib and single-agent chemotherapy for advanced lung cancer patients. Early Stage VC Provider of an online personalized digital medicine-care platform. Their flagship product, Sleepio, utilizes a digital sleep improvement program to help individuals overcome sleep related disorders. Later Stage VC Developer of microarray technologies for life science research, drug discovery, development and clinical diagnostics. The company develops an imaging and analysis system that provides sensitivity and range for protein biomarker analysis. Later Stage VC Developer of novel therapeutics for the treatment of Alzheimer's disease, dementia and other memory disorders. Early Stage VC Developer of a skin imaging device allowing patients to take two and three dimensional images of concerning lesions at home before being digitally reviewed by a dermatologist. Later Stage VC Developer of implantable intraocular lenses. The company develops accommodating intraocular lens which is designed to restore the vision of youth, middle aged or elderly individuals affected by presbyopia and cataracts.

6.11

Angel

Developer of a bio-therapeutics platform. The company develops new medicines for hypoxic diseases such as cancer, cardiovascular diseases, trauma and other conditions.

12.00

Accelerate Diagnostics, Crabtree Ventures, Leerink Partners Octopus Ventures

3.65

Undisclosed

0.50

Undisclosed

1.66

Boston Harbor Angels, other undisclosed

45.06

Aisling Capital, Correlation Venture Partners, Frazier Healthcare Ventures, Johnson & Johnson Development Corp, Advanced Technology Ventures, Lexington Capital, Medtronic, Gold Hill Capital, Venrock

4.71

Undisclosed

3

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

HQ Location

Olive Devices

26-Jul-16

Philadelphia, PA

Nomad

26-Jul-16

New York, NY

Intellirod Spine

26-Jul-16

Genome Profiling

Round

Description

Financing Size (Millions)

Early Stage VC Developer of assistive medical products for the hearing impaired 0.05 community. The company creates assistive devices and smart glasses to improve communication and personalize education for deaf and hard of hearing persons. Early Stage VC Provider of an online platform that connects doctors with freelance clinical 4.00 work. The company provides a cloud-based job marketplace for healthcare staffing that enables doctors, clinicians and medical institutions that hire them to find each other and transact directly without a broker.

BioAdvance

Akron, OH

Later Stage VC Developer of a diagnostic system for spine surgeons. The company is developing an implantable microelectronic spine fusion sensor, known as the IntelliRod system, which enables the surgeons to assess the success of spinal fusion procedures without exploratory surgery.

Queen City Angels, JumpStart

26-Jul-16

Newark, DE

Early Stage VC Provider of a platform for methylation profiling. The company's platform 0.10 enables users to transform standard next-generation deoxyribonucleic acid (DNA) sequencing data into an actionable information to make precision medicine a reality for patients afflicted with life-threatening diseases.

CellMax Life

26-Jul-16

Sunnyvale, CA

Bainbridge Health

26-Jul-16

Vtesse

25-Jul-16

Compiled by: Morgan Reape Source: Pitchbook

1.00

Early Stage VC Provider of cancer diagnostic services. The company provides 9.00 comprehensive, personalized multi-biomarker technology platforms for genetic cancer risk assessment, early detection and personalized treatment of cancer. Their flagship product, CellMax CRC-Protect, is a multibiomarker blood test for early detection of colorectal cancer. Philadedelphia, PA Early Stage VC The company provides hospitals and health systems with a clinical 0.05 intelligence and data analytics platform which allows clinicians to monitor patient safety and medication errors. Gaithersburg, MD Early Stage VC Developer of drugs for rare diseases. It has developed VTS-270 for rare 42.00 disease Niemann-Pick Disease Type C (NPC) which is in pre-clinical trials.

First Round Capital, RRE Ventures

BioAdvance

Artiman Ventures

BioAdvance

New Enterprise Associates

4

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

Tricida

25-Jul-16

Torax Medical

25-Jul-16

Svelte Medical Systems 25-Jul-16

Sansoro Health

25-Jul-16

Just Biotherapeutics

25-Jul-16

Swan Valley Medical

22-Jul-16

Roxwood Medical

22-Jul-16

HealthLynked

22-Jul-16

GoForward

22-Jul-16

Entvantage Diagnostics 22-Jul-16

Compiled by: Morgan Reape Source: Pitchbook

HQ Location

Round

Description

South San Francisco, CA

Financing Size (Millions)

Later Stage VC Operator of a bio-pharmaceutical company. The company focuses on discovery and development of first-in-class chronic therapies for patients with chronic kidney disease. Shoreview, MN Later Stage VC Developer of medical devices for the treatment of diseases related to defective sphincter muscles. The company provides a technology platform designed to restore the human sphincter function and to treat gastroesophageal reflux disease and fecal incontinence. New Providence, Later Stage VC Developer of balloon expandable stents. The company designs and NJ develops non-thrombogenic and non-inflammatory drug eluting stents for the treatment of atherosclerosis. Minneapolis, MN Seed Round Provider of an application for electronic medical record interoperability. The company's application offers assistance such as monitoring and security management of medical records. Seattle, WA Early Stage VC Designer of new technologies for bio-therapeutic development. The company develops integrated design frameworks, impacting speed, cost of developing and manufacturing biologics. Bigfork, MT Later Stage VC Manufacturer of disposable surgical instruments and accessories that are used for the treatment of suprapubic bladder catheterization. Redwood City, CA Later Stage VC Developer of novel front-line catheters to help patients with severe coronary and peripheral arterial disease. Its unique MultiCross and CenterCross platforms utilize patented Nitinol scaffolds to provide ultimate guidewire support for the interventional cardiologist. Naples, FL Angel Provider of a personal electronic medical records system. The company's platform allows patients to archive their medical records in coordination with their physician. San Francisco, CA Angel Developer of a sensor based technology.

55.00

Longitude Capital

25.00

Undisclosed

54.40

Clark Enterprises

1.20

Healthy Ventures

14.00

The Bill & Melinda Gates Foundation

0.03

Undisclosed

6.46

Undisclosed

3.92

Undisclosed

30.00

Austin, TX

1.45

Eric Schmidt, Marc Benioff, Aaron Levie Undisclosed

Angel

Developer of diagnostic test kits. The company provides physicians with timely information on the cause of ear, nose and throat illnesses with inoffice diagnostic tests.

5

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

HQ Location

Apama Medical

22-Jul-16

Campbell, CA

Seremedi

21-Jul-16

Houston, TX

Saykara

21-Jul-16

Seattle, WA

N-of-One

21-Jul-16

Lexington, MA

InflaRx

21-Jul-16

Jena, Germany

FlexDex

21-Jul-16

Brighton, MI

ESO Solutions

21-Jul-16

Austin, TX

Direct Flow Medical

21-Jul-16

Creo Wellness

21-Jul-16

Compiled by: Morgan Reape Source: Pitchbook

Round

Description

Later Stage VC Developer of medical devices focused on the treatment of atrial fibrillation. The company develops a catheter ablation approach designed to increase procedural efficiency and safety, addressing obstacles to widespread adoption of atrial ablation therapy. Seed Round Provider of a patient engagement platform which allows healthcare providers to prescribe guided treatment plans through mobile devices.

Financing Size (Millions)

9.03

Undisclosed

1.70

Undisclosed

Seed Round

Developer of a healthcare technology platform used as a personal assistant 2.53 for physicians. Later Stage VC Provider of clinical interpretation of molecular tests in oncology. The 7.00 company provides clinical analysis, curation and interpretation of a tumor's molecular profile to diagnostic companies, individual physicians and patients. Later Stage VC Developer of therapeutics in the field of acute and chronic inflammation. 34.85 The company focuses on the general area of inflammation including indications such as SIRS and SEPSIS by applying therapeutics in order to prevent organ dysfunction or limit progression into organ failure.

Madrona Venture Group Providence Ventures, Excel Venture Management Staidson Hongkong Investment

Angel

1.50

Undisclosed

17.66

Accel-KKR

Santa Rosa, CA

Provider and developer of minimally invasive surgical devices and technologies that enhance dexterity and reduce surgeon-training time and cost. PE Growth/ Provider of medical record management services. The company offers Expansion electronic patient care reporting software and billing services to EMS and fire organizations that enable emergency medical responders to capture patient data during emergency visits. Later Stage VC Manufacturer of medical transcatheter aortic valve systems.

27.10

SV Life Sciences

Henrico, VA

Angel

2.25

Undisclosed

Operator of a platform that uses blood testing and precision analytics to offer personalized coaching and employee plans to minimize employee healthcare costs.

6

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

HQ Location

Round

Description

Consensus Orthopedics 21-Jul-16

El Dorado Hills, CA

PE Growth/ Expansion

Clinipace Worldwide

21-Jul-16

Morrisville, NC

PE Growth/ Expansion

AristaMD

21-Jul-16

La Jolla, CA

Topical Remedy

20-Jul-16

Lake Oswego, OR

Synthorx

20-Jul-16

La Jolla, CA

Synapsin Pharmaceuticals

20-Jul-16

Columbia, SC

Early Stage VC Operator of a referral management system with tools for facilitating specialty referrals to meet the needs of primary and specialty care physicians. Angel Provider of a clinical trial treatment for an undisclosed skin disease. The company enables specific patented treatment protocol for a specific disease. Early Stage VC Developer of therapeutics, diagnostics and vaccines using synthetic biology. The company develops proteins, RNA and DNA for medical applications using synthetic nucleotide that can be maintained and replicated by a single-cell organism. Angel Developer of therapeutic drugs to treat neuro-degenerative disorders such as Alzheimer's disease, Parkinson's disease and spinal cord injury.

Rivanna Medical

20-Jul-16

Charlottesville, VA Early Stage VC Developer of a medical imaging device based on medical ultrasound. The company has developed Accuro, an imaging product for spinal anesthesia guidance and diagnostic imaging of the cardiac and abdominal anatomies.

Paratus Diagnostics

20-Jul-16

Austin, TX

Compiled by: Morgan Reape Source: Pitchbook

Manufacturer of joint orthopedic implant devices. The company manufactures knee systems, hip systems, knee cups and other joint implants and instruments. Provider of technology-based clinical research services for clinical trials, registries, grants management and investigator initiated studies. The company, through its web-based software platform, provides research services such as project management, monitoring, site management, data management, supply management and biostatistics.

Financing Size (Millions)

1.00

Undisclosed

3.73

Undisclosed

11.00

Avalon Ventures

0.50

Undisclosed

10.00

RA Capital Management

0.38

Undisclosed

0.37

Undisclosed

Early Stage VC Provider of a portfolio of point of care diagnostic devices and services that 2.80 will help in patient testing for infectious diseases.

Undisclosed

7

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

HQ Location

MedAware

20-Jul-16

Ra'anana, Israel

Docent Health

20-Jul-16

BodySpec

Round

Description

Financing Size (Millions)

DreamIt Ventures

Boston, MA

Provider of a technology for eliminating prescription errors. The 1.30 company's technology uses big data analytics and machine learning algorithms to analyze electronic medical records and flag potentially flawed prescriptions. Early Stage VC Developer of software and mobile applications for patient record 17.10 monitoring. The company's platform combines analytics with workflow automation to allow health systems to personalize experience journeys that integrate digital and human interactions while gathering data and measuring results to identify the most impactful events.

20-Jul-16

Los Angeles, CA

Angel

Undisclosed

Akili Interactive Labs

20-Jul-16

Boston, MA

PureTech Ventures

Virta Health

19-Jul-16

San Francisco, CA

Early Stage VC Developer of mobile video games for cognitive therapy and treatment. The 42.40 company's product helps improve conditions like depression or attention deficit disorder. Early Stage VC Developer of clinical therapies for the treatment of chronic diseases. The 28.78 company combines advanced biochemistry and clinical expertise with data science and digital tools in order to develop therapies to restore metabolic health for patients dealing with a range of chronic diseases.

Vensica Medical TeraBAT

19-Jul-16 19-Jul-16

Tel Aviv, Israel Niwot, CO

Angel PE Growth/ Expansion

Undisclosed Undisclosed

Reflexion Medical

19-Jul-16

Hayward, CA

Compiled by: Morgan Reape Source: Pitchbook

Accelerator/ Incubator

Developer of DXA scan technology to test body fat. The company 0.60 provides full body composition analysis, body fat percentage, muscle mass, bone density and resting metabolic rate using its DXA scan technology.

Developer of an ultrasound-assisted drug-delivery catheter. 0.50 Developer of a disruptive detection platform based on terawaves 1.05 technology. The company provides a platform that specializes in disease detection, disease diagnosis, breath analysis, exhaled breath biomolecule identification and patient care. Early Stage VC Developer of a biologically-guided radiation therapy system to be used for 52.00 treating solid tumors throughout the body.

Bessemer Venture Partners

Undisclosed

KCK Group

8

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

Precision Ocular

19-Jul-16

Oncorus

19-Jul-16

InfoBionic

19-Jul-16

Immutrix Therapeutics 19-Jul-16

HealthCall

19-Jul-16

Fulcrum

19-Jul-16

ForSight Vision6

19-Jul-16

Eyenuk

19-Jul-16

Compiled by: Morgan Reape Source: Pitchbook

HQ Location

London, United Kingdom

Round

Description

Early Stage VC Developer of a drug-based treatment for retinal diseases, including agerelated macular degeneration, diabetic macular edema, retinal vein occlusion, uveitis and cystoid macular edema. Cambridge, MA Early Stage VC Developer of a next-generation immunotherapy platform for the treatment of cancer. The company develops next generation oncolytic vectors for the treatment of several tumor types including highly malignant and aggressive cancers such as glioblastoma multiforme. Lowell, MA Early Stage VC Developer of the MoMe System, a patient-monitoring platform that includes a cloud-based architecture for analysis, a patient device and a physician-user interface for remote management. Its initial product will be focused on detecting cardiac arrhythmias. Rapid City, SD Angel Developer of medical products to modulate and sequester molecules from blood. The company develops medical products that seek to remove inflammatory mediators and toxins from the patient's blood in order to alter the therapeutic outcomes of treatments. Crown Point, IN Later Stage VC Provider of automated patient response systems for use in disease management. The company's cloud based system enables the communication of information between healthcare professionals and patients by providing scheduling, decision support, authentication, access encryption, standardized documentation, audit trails and transaction management tools. Cambridge, MA Early Stage VC Developer of small molecules that modulate the on/off control mechanisms of genes. The company develops medicines to deliver a new future to patients and their families by transforming gene regulation in disease and unlocking gene control mechanisms. Menlo Park, CA Early Stage VC Developer of ophthalmic products to improve the sight, care and life of visually impaired patients. The company offers products for the treatment of glaucoma for adult irreversible blindness. Woodland Hills, CA Angel Developer of computer vision, retinal image analysis and machine learning technologies for medical and consumer domains.

Financing Size (Millions)

22.08

Imperial Innovations Group

57.00

MPM Capital

8.20

Safeguard Scientifics

4.09

Undisclosed

0.10

Undisclosed

55.00

Third Rock Ventures

3.50

Undisclosed

1.50

Undisclosed

9

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

Coriell Life Sciences

19-Jul-16

BioSculpture Technology

19-Jul-16

Altor BioScience

19-Jul-16

PamBio

HQ Location

Round

Description

0.61

Undisclosed

0.28

Undisclosed

20.00

Undisclosed

18-Jul-16

Early Stage VC Provider of a healthcare management system for patients and physicians. The company offers storage of genomic data, expert interpretation and an interchange framework that delivers clinically-relevant genomic interpretation at the point-of-care. West Palm Beach, Angel Manufacturer of minimally invasive medical devices and methods for FL endoscopic visceral lipectomy as a new treatment of obesity, metabolic syndrome and Type 2 diabetes mellitus. Miramar, FL Later Stage VC Developer of immunotherapeutic products for the treatment of cancer, viral infections and autoimmune diseases. Nazareth Illit, Israel Angel Developer of a drug therapy for acute bleeding conditions.

7.00

Undisclosed

Milo (BAC Monitor)

18-Jul-16

Santa Barbara, CA

Angel

0.20

Undisclosed

Micro C

18-Jul-16

Savannah, GA

Seed Round

0.26

Undisclosed

Magnetic Insight

18-Jul-16

Alameda, CA

Seed Round

3.00

Sand Hill Angels

Laxmi Therapeutic Devices Kailos Genetics

18-Jul-16

Goleta, CA

Seed Round

1.50

Undisclosed

18-Jul-16

Huntsville, AL

Angel

Invenra

18-Jul-16

Madison, WI

Diamedica (DMA)

18-Jul-16

Minneapolis, MN

Compiled by: Morgan Reape Source: Pitchbook

Camden, NJ

Financing Size (Millions)

Developer of a wearable alcohol sensor. The company monitors blood alcohol levels through perspiration which can be paired and tracked through a smartphone. Developer of a fluoroscopic instrument. The company develops an agile instrument that incorporates an x-ray and digital camera for use in surgical and non-surgical procedures. Developer of a molecular imaging technology. The company develops a functional imaging modality where real time biological events can be monitored verses anatomical imaging. Operator of a medical device company.

Provider of custom enrichment services to the DNA and drug research market, including reference lab services, reagents and licensing via an LIS system, and a service for patients to order pharmacogenetic or hereditary cancer tests with physician authorization. Early Stage VC Developer of a platform to screen peptides and proteins to discover and develop new biologic drugs in areas like cancer, Alzheimer's disease and diabetes.

Undisclosed Undisclosed

5.01

Wisconsin Investment Partners, other undisclosed

PIPE

4.00

Hermed Capital

Developer of drugs to treat diabetes and related diseases.

10

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

HQ Location

Round

Description

Financing Size (Millions)

Cambridge Medical Robotics

18-Jul-16

Cambridge, United Early Stage VC Developer of a robotic system for minimal access surgery. Kingdom

20.30

WellBrain

15-Jul-16

Pleasant Hill, CA

Accelerator/ Incubator

0.35

seqWell

15-Jul-16

Beverly, MA

Angel

Sequentia

15-Jul-16

Cleveland, OH

Medsphere Systems

15-Jul-16

Carlsbad, CA

LifeDojo

15-Jul-16

San Francisco, CA

Lab Sensor Solutions

15-Jul-16

Redwood City, CA Accelerator/ Incubator

Developer of a mobile sensor platform that provides real-time location tracking and temperature monitoring of lab samples and pharmaceuticals. It also develops Internet of Things Sensors for the healthcare industry.

Undisclosed Launchpad Digital Health

Hint Health

15-Jul-16

San Francisco, CA

Developer of a membership management and billing platform for direct care, direct primary care and concierge medicine providers.

Undisclosed StartX, Launchpad Digital Health

Compiled by: Morgan Reape Source: Pitchbook

Provider of evidence-based treatment to patients with chronic pain, depression, anxiety, substance abuse, and other mental health disorders.

Provider of DNA sequencing services. The company performs all preparation, sequencing and data processing on site, along with customized bioinformatics support. Angel Developer of an online platform that enables patients and families, hospitals and physician groups and extended care providers to connect and search for each other. Later Stage VC Provider of an open-source electronic health-record system designed to encourage clinician adoption, facilitate workflow automation and foster interoperability. Early Stage VC Developer of an online wellness platform for employees. The company develops behavior change training applications for stress reduction, healthy eating, exercise, brain science, and happiness for professionals in businesses, schools, non-profit organizations, and health institutions.

Accelerator/ Incubator

ABB Technology Ventures, LGT Group, Cambridge Innovation Capital Launchpad Digital Health

1.29

Undisclosed

1.25

Undisclosed

15.30

Undisclosed

0.88

Swanhill Capital, Launchpad Digital Health, Telluride Venture Fund

11

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

HQ Location

Round

Description

Endonovo Therapeutics 15-Jul-16 (ENDV)

Woodland Hills, CA PIPE

Azalea Health

15-Jul-16

Atlanta, GA

MindImmune Therapeutics

14-Jul-16

Rhode Island

microDimensions

14-Jul-16

Munich, Germany

Early Stage VC Provider of software and services for digital pathology applications. The Undisclosed Adriaan Hart de company's software provides image analysis, 3D histology reconstruction, Ruijter, High-Tech protein multiplexing, stereology and image registration for e-assessment of Gründerfonds, histological specimens. It provides analysis, registration, reconstruction and Bayern Kapital visualization services of microscopic and digital pathology data.

Joylux

14-Jul-16

Seattle, WA

Seed Round

Immunome

14-Jul-16

Philadelphia, PA

Genomind

14-Jul-16

King of Prussia, PA Later Stage VC Developer of neuropsychiatric disease biomarker tests such as the Genecept Assay, a genetic test designed to help clinicians optimize treatment decisions for their patients with mental illness.

Compiled by: Morgan Reape Source: Pitchbook

Developer of bioelectronic devices and therapies for regenerative medicine. The company develops therapies to treat acute and chronic diseases and offers non-invasive bioelectronics to stimulate the body's natural repair system to treat injuries and inflammatory diseases.

Financing Size (Millions)

Later Stage VC Provider of cloud-based healthcare technologies and services. The company provides an electronic health records system for medical practices, including scheduling, charting, e-prescribing, billing, laboratory ordering and reporting. Seed Round Developer of drugs to treat diseases of the central nervous system, including Huntington disease, Alzheimer's, pain and psychiatric disorders.

10.00

Bellridge Capital

10.50

Kayne Anderson Capital Advisors

0.50

Slater Technology Fund

Developer of medical devices and therapeutic systems. The company 3.78 specializes in developing a medical instrument called VSCULPT for rejuvenation of the vaginal tissue and pelvic floor toning. Later Stage VC Developer of novel immunotherapies and cancer therapeutics products 5.06 produced by an immunotherapy discovery engine. Its proprietary RealMAb technology enables the simultaneous discovery of novel antigens and the cognate native human antibodies that target those antigens. 20.95

Undisclosed

Undisclosed

Capital Alighnment Partners

12

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

HQ Location

Round

Description

Financing Size (Millions)

Endotronix

14-Jul-16

Woodridge, IL

Later Stage VC Provider of cardiac monitoring services. The company develops wireless sensors to monitor the condition of patients with congestive heart failure.

32.00

Titan Spine

13-Jul-16

Mequon, WI

TesoRx

13-Jul-16

Pomona, CA

PE Growth/ Designer and manufacturer of spinal inter-body fusion implants. Expansion Later Stage VC Provider of unmodified oral testosterone for androgen deficiency. The company develops a proprietary delivery system for testosterone that is intended to deliver the hormone at normal physiological levels.

Undisclosed Southlake Cequity Group 0.70 Undisclosed

Second Genome

13-Jul-16

South San Francisco, CA

Later Stage VC Provider of microbial profiling services for life science researchers to identify and understand microbial signatures of human diseases.

51.00

Pfizer Venture Investments, Roche Venture Fund

Miramar Labs

13-Jul-16

Santa Clara, CA

Later Stage VC Manufacturer of electromechanical devices for cosmetic surgeries.

9.38

Magnolia Medical Technologies

13-Jul-16

Seattle, WA

Deciphera Pharmaceuticals

13-Jul-16

Waltham, MA

CarePredict

13-Jul-16

Plantation, FL

Later Stage VC Provider of methods to reduce blood culture sample contamination. The 13.80 company develops a self-contained system focused on improving patient safety, reducing expenses and increasing hospital bed availability by decreasing false positive blood cultures. Later Stage VC Developer of kinase-inhibiting drugs for the treatment of cancers and 90.60 immunological diseases. The company develops therapeutic agents against leukemia, invasive cancers, melanoma, gastrointestinal stromal tumors, bone metastases and autoimmune diseases. Early Stage VC Manufacturer of a wrist-worn sensor with an embedded software that 1.31 tracks normal daily activities of senior citizens to detect their health conditions.

Aisling Capital, other undisclosed HealthQuest Capital

Caremerge

13-Jul-16

Chicago, IL

Compiled by: Morgan Reape Source: Pitchbook

Later Stage VC Developer of mobile and Web applications to improve communications and care coordination in the senior healthcare industry.

14.00

SV Life Sciences

New Leaf Venture Partners

Westlake Ventures, Las Olas Venture Capital, other undisclosed Insight Venture Partners

13

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

HQ Location

Augmenix

13-Jul-16

Waltham, MA

Adient Medical

13-Jul-16

Pearland, TX

Stocosil

12-Jul-16

Industry, CA

Sienna

12-Jul-16

Westlake Village, CA

Sapience Therapeutics

12-Jul-16

Prodontis

Round

Description

6.00

Undisclosed

1.47

Undisclosed

2.03

Undisclosed

46.00

ARCH Venture Partners, Partner Fund Management

Scarsdale, NY

Early Stage VC Developer of novel therapeutics for major unmet medical needs, 22.50 particularly high mortality cancers. The company's initial goal is to develop a first-in-class treatment for glioblastoma multiforme, the most severe and deadly form of brain cancer, as well as other oncology indications.

Eshelman Ventures

12-Jul-16

Limoges, France

Angel

Lyndra

12-Jul-16

Cambridge, MA

Undisclosed

Lemonaid Health

12-Jul-16

San Francisco, CA

Jupiter Orphan Therapeutics Invicta Medical

12-Jul-16

Jupiter, FL

Early Stage VC Developer of an extended drug release technology that extends oral drug 5.93 delivery beyond one week and improves adherence, pharmacokinetic profiles, benefits convenient patient experience, decreases antibiotic resistance potential and reduces healthcare costs. Angel Provider of an online telemedicine platform that allows patients to contact 1.71 and consult doctors online using its application. Angel Developer of therapies for rare diseases linked to single gene deficiencies. 0.25

12-Jul-16

Palo Alto, CA

Early Stage VC Developer of a therapeutic wearable device that treats patients suffering from sleep apnea and snoring diseases.

Undisclosed

Compiled by: Morgan Reape Source: Pitchbook

Later Stage VC Developer of hydrogel-based medical devices for radiation oncology and cancer surgery. The company develops implantable bio-material based devices for radiotherapy safety. Its product is an injectable tissue spacer that decreases rectal morbidity in prostate radiotherapy. Accelerator/ Developer of implantable and absorbable medical devices. Incubator Angel Developer of anti-hypertension drugs. The company specializes in developing personalized dosing for anti-hypertension. Early Stage VC Developer of medical dermatology products. The company is focused on the discovery, clinical development and commercialization of products in aesthetics and dermatology based on scientific breakthroughs that improve patient outcomes and physicians' practice of medicine.

Financing Size (Millions)

Developer of a dental device for cleaning teeth. The company designs and Undisclosed Femmes Business develops medical dental devices that treat patients with periodontitis. Angels

5.47

Undisclosed Undisclosed

14

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

GC Aesthetics

12-Jul-16

BliNK Biomedical

12-Jul-16

Anagin

12-Jul-16

Advantagene

12-Jul-16

Vigilant Biosciences

11-Jul-16

TransMedics

HQ Location

Round

Description

Later Stage VC Manufacturer and distributor of breast implants, medical esthetics, nagor implants, augmentation products and cosmetic surgery devices. Lyon, France Early Stage VC Developer of novel antibiotic and research services for monoclonal antibodies. The company focuses on the discovery and development of novel therapeutic antibodies in oncology and immuno-oncology. Indianapolis, IN Angel Developer of a therapy for post traumatic distress syndrome. The company develops a drug targeting post traumatic distress syndrome without triggering other side effects. Auburndale, MA Angel Operator of a biopharmaceutical company focused on preventing the recurrence and progression of cancer through the use of therapeutics in oncology and immunotherapy. Fort Lauderdale, FL Angel Developer of a medical technology to detect oral cancers at an early stage and improve overall survival rates.

20.00

11-Jul-16

Andover, MA

Later Stage VC Developer of organ transplant technologies called an Organ Care System designed to maintain organs in a warm, functioning state outside of the body during transfer from organ donor to recipient.

63.73

Sermonix Pharmaceuticals

11-Jul-16

Columbus, OH

Seed Round

1.55

Prelude Therapeutics

11-Jul-16

Newark, DE

Angel

Compiled by: Morgan Reape Source: Pitchbook

Dublin, Ireland

Financing Size (Millions)

Operator of a specialty pharmaceutical company offering healthcare products in women’s health, menopause and selective estrogen receptor modulators. Operator of a biotechnology company. The company specializes in the research and development of medicines targeting chromatin function to treat cancer and rare diseases.

6.35

Montreux Equity Partners Idinvest Partners, other undisclosed

0.95

Undisclosed

12.89

Undisclosed

5.00

White Owl Capital, venVelo, Florida Institute for the Commercialization of Public Research Fayerweather Fund, InBio Ventures, Ervington Investments, BioStar Ventures

5.00

Dr. Anthony H. Wild, other undisclosed Undisclosed

15

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

HQ Location

Round

iQuartic

11-Jul-16

Boston, MA

Angel

ImmunArray

11-Jul-16

Richmond, VA

Later Stage VC

CrossTx

11-Jul-16

Bozeman, MT

Angel

Avizia

11-Jul-16

Reston, VA

Early Stage VC

Acticor Biotech

11-Jul-16

Paris, France

Angel

Abingdon Health

11-Jul-16

York, United Kingdom

Later Stage VC

RSP Systems

8-Jul-16

Odense, Denmark

Angel

Recombinetics

8-Jul-16

St. Paul, MN

Later Stage VC

MTrap

8-Jul-16

Huntington, NY

Early Stage VC

Compiled by: Morgan Reape Source: Pitchbook

Description

Provider of a technology platform that aggregates real-time electronic medical record (EMR) data from multiple clinical care settings. The company gives health care groups access to organized and homogenized EMR data from disparate systems and produces EMR derived results through analytics and mining. Developer of an in-vitro diagnostic platform system. The company is dedicated to the development of microarray devices and informatics that are used in profiling a patient's immune system, allowing the physicians to detect autoimmune, lung cancer and other diseases. Provider of referral management and chronic condition management software. Developer of a platform that allows medical experts to reach out to their patients through telemedicine. It also provides workflow management software, store-and-forward capabilities with electronic health record integration and a line of peripherals, such as digital stethoscopes and examination cameras. Provider of therapeutic services for the treatment of emergency stroke. The company develops the anti-GPVI antibody as a platelet-aggregation inhibitor for acute thrombotic pathologies. Provider of medical diagnostic tools and services. The company is focused on developing a range of rapid testing products in the area of hematologyoncology. Developer of glucose monitoring devices for diabetic patients and minispectrometers. Developer of gene editing technologies. The company manipulates the deoxyribonucleic acid (DNA) sample to add and activate genes to solve problems in biomedical research, livestock productivity and animal-derived biomaterials for use in medical applications. Owner and operator of a biotechnology company.

Financing Size (Millions)

0.81

Undisclosed

10.00

Exigent Capital

0.66

Undisclosed

14.11

Blue Heron Capital

1.57

Anaxago, ARMESA, other undisclosed

4.27

Imperial Innovations Group

5.17

Roland Berger

5.66

Undisclosed

6.00

Deerfield Management

16

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

HQ Location

Round

Description

Financing Size (Millions)

Horama

8-Jul-16

Paris, France

3Scan

8-Jul-16

San Francisco, CA

Reconstruction Innovation National HME

7-Jul-16

New Albany, MS

7-Jul-16

Richland Hills, TX PE Growth/ Expansion

2.84

Undisclosed

Gogo Band

7-Jul-16

Ashland, VA

0.07

Undisclosed

Ascendant Dx

7-Jul-16

Springdale, AR

0.38

Undisclosed

AnTolRx United Therapies

7-Jul-16 6-Jul-16

Boston, MA Des Plaines, IL

1.00 0.97

Undisclosed Undisclosed

Compiled by: Morgan Reape Source: Pitchbook

Early Stage VC Developer of gene therapies for the treatment of hereditary retinal 4.50 dystrophies. The company develops innovative gene therapy products for the treatment of rare ophthalmological diseases, orphan hereditary recessive retinitis pigmentosa and rare ophthalmic pathologies to preserve visual autonomy of the affected patients. Later Stage VC Developer of diagnostic and therapeutic discovery applications. The 14.00 company develops KESM (Knife Edge Scanning Microscope) technology to automatically section and image samples. Its robotic microscopy tools and software are generally used for large-scale sample analysis and 3D visualizations. Angel Developer of a technology for joint surgeries. 0.30 Provider of outsourced medical equipment management services to the hospice market. It also offers respiratory and mobility equipment, including oxygen concentrators and cylinders, commodes, shower chairs and gastric suction equipment. Angel Developer of a biometric device to cure pediatric enuresis. The company develops a wearble device that uses biometric telemetry such as heart rate, body temperature and skin conductivity to alarm children prior to urination. Later Stage VC Developer of proteomics-based diagnostic tests focused on areas of diagnostics where conclusive diagnostic tests are not yet available, including breast cancer. Angel Owner and operator of a biotechnology company. PE Growth/ Supplier of surgical equipment to medical centers and hospitals. The Expansion company operates lithotripter units and specializes in urological laser treatments, general surgery, neurosurgery, ophthalmology and orthopedic surgery.

Omnes Capital, Sham Innovation Santé, GO Capital

Lux Capital, Data Collective

Undisclosed

17

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

HQ Location

Round

Description

Financing Size (Millions)

Personalized Cancer Therapy

6-Jul-16

McLean, VA

Early Stage VC Provider of a personalized cancer therapy service. The company provides personalized cancer profiling to advanced stage cancer patients and their oncologists to determine suitable cancer treatment options.

9.17

Pilot Growth Equity

Palleon Pharma

6-Jul-16

Cambridge, MA

Angel

8.60

Undisclosed

Cynapsus Therapeutics 6-Jul-16 (CTH)

Develper of drugs for diseases characterized by dysregulation of the innate immune system. Toronto, Canada PIPE Developer of drugs to treat the motor symptoms of Parkinson’s disease. The company is engaged in developing a sublingual thin filmstrip to manage complexities associated with Parkinson’s disease. Cologne, Germany Early Stage VC Developer of a cryotherapy system for the treatment of coronary artery disease. The company is developing a novel catheter system utilizing cryoenergy to treat and prevent heart attacks. Norwalk, CT Angel Developer of a therapeutic device for stroke treatment that works as an automated external defibrillator during a stroke. Baltimore, MD Seed Round Developer of a cloud-based platform enabling analysis and review of biopsy slides.

Undisclosed OrbiMed Advisors

CryoTherapeutics

6-Jul-16

Vesselon

5-Jul-16

Proscia

5-Jul-16

NightBalance

5-Jul-16

Delft, Netherlands Later Stage VC Developer of a technology to treat sleep apnea. The company offers Sleep 14.05 Position Trainer, a proprietary device that measures the sleep behavior of the patient and prevents positional obstructive sleep apnea.

LabDoor

5-Jul-16

South San Francisco, CA

Knopp Biosciences

5-Jul-16

Pittsburgh, PA

Compiled by: Morgan Reape Source: Pitchbook

5.85

Creathor Venture

0.23

Undisclosed

1.00

Emerald Development Managers INKEF Capital, Glide Healthcare Partners

Early Stage VC Provider of online dietary supplements. The company analyzes the purity 4.34 and potency of hundreds of dietary supplements and energy drinks at FDAregistered labs and then offers them online at its website and via its mobile application. Later Stage VC Developer of drugs for neurological disorders, such as Amyotrophic lateral 14.94 sclerosis, Parkinson's disease and other neuro degenerative disorders.

Undisclosed

Saturn Management, Innovation Works, other undisclosed

18

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

HQ Location

Round

Financing Size (Millions)

Concord Biotech

5-Jul-16

Ahmedabad, India

Capnia (CAPN)

5-Jul-16

Redwood City, CA PIPE

ASLAN Pharmaceuticals

5-Jul-16

Singapore, Singapore

Wellness Warehouse

4-Jul-16

Pharmacy2U

4-Jul-16

Cape Town, South Later Stage VC Operator of an online selling portal of healthcare and wellness products. Undisclosed Leaf Captial Africa The company runs an online retail outlet that provides a wide range of products and services for a lifestyle of wellness. Leeds, United PE Growth/ Operator of an online pharmacy business. The company offers self14.24 Business Growth Kingdom Expansion managed electronic prescription services, enabling patients to manage their Fund NHS prescriptions online. It also offers national mail order, e-commerce and m-commerce services as well as GP consulting services.

Nyxoah

4-Jul-16

CStone

4-Jul-16

Compiled by: Morgan Reape Source: Pitchbook

PE Growth/ Expansion

Description

PE Growth/ Expansion

Provider of biotechnological research and development services. The Undisclosed Quadria Capital company manufactures active pharmaceutical ingredients through the Investment process of fermentation, semi-synthetic and synthetic processes and deals Management, Helix in diverse therapeutic segments. Investments Developer of novel therapeutic and diagnostic products. The company 3.15 Undisclosed offers a handheld device that provides therapy for migraine headaches and allergies. It also commercializes a medical device to detect carbon monoxide levels in the breath. Developer of novel medicines for oncology and inflammation diseases. It 23.00 DAIWA Corporate also develops a portfolio of immunotherapies and targeted drugs, focusing Investment, KGI on Asia prevalent tumor types. VC, Milestone Capital Advisors, Taya Ventures, Top Taiwan Venture Captial Group

Mont-Saint-Guibert, Later Stage VC Developer of a neurostimulation device for treating patients suffering from 20.00 Belgium obstructive sleep apnea. Shanghai, China Early Stage VC Developer of new treatments for chronic diseases. The company is 150.00 focused on the development of treatments for oncology, cardiovascular diseases, rheumatoid arthritis, hematology and autoimmune diseases.

Glide Healthcare Partners, Novallia Boyu Capital Advisory Company, Oriza Holadings, Wuxi Venture Fund

19

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Two Pore Guys

Last Financing Date

HQ Location

1-Jul-16

Santa Cruz, CA

SimpleHealth Ventures 1-Jul-16

New York, NY

Serenity Pharmaceuticals

1-Jul-16

Brooklyn, NY

Revalesio HealthCure

1-Jul-16 1-Jul-16

Tacoma, WA Ann Arbor, MI

G1 Therapeutics

1-Jul-16

Durham, NC

Fluorofinder

1-Jul-16

Broomfield, CO

DreaMed Diabetes

1-Jul-16

Petah Tikva, Israel

CoRNerstone Healthcare Solutions (Healthcare Company)

1-Jul-16

Wichita, KS

Compiled by: Morgan Reape Source: Pitchbook

Round

Angel

Description

Developer of solid state nanopore technologies for biosensors that can examine molecules and polymers used for applications ranging from genome sequencing to medical diagnostics. Seed Round Provider of a cloud-based credentialing platform. The company helps in creating revenue generation opportunity for the hospital and alleviates staff work while reducing the amount of time required to complete primary source verification through secure online services. Angel Developer of pharmaceuticals using delivery mechanisms combined with low threshold efficacious formulations to engineer drugs with minimal side effects. Angel Developer of anti-inflammatory therapeutics. Later Stage VC Provider of services to combat the sources of hospital-acquired infections. The company provides healthcare facilities with monitoring and disinfectant applications to assess and reduce facility microbial burdens.

Financing Size (Millions)

5.18

Undisclosed

2.74

Bowery Capital

7.89

Undisclosed

14.00 2.50

Undisclosed Undisclosed

Later Stage VC Developer of small molecule therapeutic agents that are aimed at 50.00 protecting bone marrow, kidneys and other organs from damage caused by chemotherapy and radiation therapy. Angel Provider of an online tool to design medical research experiments. The 3.42 company provides a cloud-based experiment design tool that enables scientists to select the best fluorochromes for their medical research experiments. Angel Developer of a software for the treatment and management of diabetes. 3.30 The company is the developer of a closed-loop insulin-delivery sitter, which involves an automated device that uses input data from the sensor of an insulin-dependent diabetes patient, analyzes it and commands the pump to deliver the correct dose of insulin at the right time. Seed Round

Cormorant Asset Management Undisclosed

Norma Investments, other undisclosed

Provider of an online platform to compare healthcare pricing. The Undisclosed Undisclosed company focuses on combining healthcare technology required for patientcentered medical care.

20

Monthly Healthcare Review July 2016 Private Equity Placements and Venture Capital Rounds The following table includes institutionally placed private equity financings for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Lead Investor(s) Last Company Name

Last Financing Date

HQ Location

AnatoMotion

1-Jul-16

Austin, TX

AGH Therapeutics 3-V Biosciences

1-Jul-16 1-Jul-16

Nashville, TN Menlo Park, CA

Compiled by: Morgan Reape Source: Pitchbook

Round

Angel

Description

Developer of hardware and software products for dental motion analysis. The company develops motion sensors for the monitoring of dental bite problems associated with issues such as sleep apnea, grinding teeth and TMJ problems. Angel Provider of pharmaceutical products and services. Later Stage VC Developer of novel therapeutics that modulate key pathways for the treatment of oncology and infectious disease.

Financing Size (Millions)

0.51

Crowdfunder

0.60 5.44

Undisclosed Undisclosed

21

Monthly Healthcare Review July 2016 Mergers and Acquisitions The following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Acquirer

Target

HQ Location

Date

Description

Transaction Value (Millions)

Boston Scientific

Cosman Medical

Burlington, MA

27-Jul-16

Manufacturer of radiofrequency ablation systems. The company engages in the development of electrosurgical generators and probes such as RF generators, RF Cannulae & Electrodes, RF Cannulae & Electrodes and others.

Undisclosed

NXT-ID

LogicMark

Louisville, KY

26-Jul-16

20.90

Espada Dermatology

GlyDerm

Summit, NJ

26-Jul-16

The Surgical company

Sensium Healthcare Abingdon, United 22-Jul-16 Kingdom Micromed Mogliano Veneto, 22-Jul-16 Italy Medisafe UK Bishop's Stortford, 22-Jul-16 United Kingdom

Designer and manufacturer of unmonitored personal emergency response devices that utilize 2-way voice communication technology. Its product line is specifically used by the elderly or those with serious medical issues who wear a pendant with a speakerphone and can push a button to call for help. Provider of dermatological products. The company produces and retails physiciandispensed skincare products to customers for problems related to dry, itchy skin, acne, and dermatitis. Provider of a wireless vital signs monitoring system for use in hospital general wards and emergency departments. Manufacturer of electromedical devices used for neurophysiology diagnostics.

ArchiMed Steris

Royal Philips

WellCentive

Hansa Medical

Immago Biosystems Cheltenham, United 19-Jul-16 Kingdom

Zimmer Biomet

Medtech (surgical robots)

Compiled by: Morgan Reape Source: Pitchbook

Alpharetta, GA

20-Jul-16

Montpellier, France 18-Jul-16

Undisclosed

1.85 Undisclosed

Manufacturer of surgical reprocessing equipment. The company is engaged in the 38.45 production of equipment, associated consumables and accessories such as washer disinfectors, endoscopy reprocessing, dental products and bed pan washers. Provider of population health management and data analytics services. The company transforms actionable data into meaningful information that enables preventive care, evidence-based chronic disease management, clinical integration and participation in performance-based and risk-based reimbursement programs including Pay-for-Performance and Accountable Care.

Undisclosed

Developer of antibody-based cancer therapies. The company develops and Undisclosed markets therapeutic antibodies arising from work in the Glycobiology by using antibody-modulating enzymes for antibody based cancer treatments. Developer and manufacturer of surgical robots to assist physicians during surgical 132.00 interventions. The products developed by the company incorporate planning software with a robotized platform and visualization systems based on diagnostic capabilities.

22

Monthly Healthcare Review July 2016 Mergers and Acquisitions The following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Acquirer

Target

HQ Location

Date

Carlton-Harvey Group Firefly Medical

Fort Collins, CO

18-Jul-16

Undisclosed

Datatrial

18-Jul-16

Sartorius

ViroCyt

Newcastle upon Tyne, United Kingdom Broomfield, CO

Terumo

Sequent Medical

Aliso Viejo, CA

14-Jul-16

Alliance for Lupus Research Juno Therapeutics

S.L.E. Lupus Foundation RedoxTherapies

New York, NY

14-Jul-16

Boston, MA

14-Jul-16

Recordati

Pro Farma

Baar, Switzerland

14-Jul-16

Ximedica

Accel Biotech

Los Gatos, CA

14-Jul-16

Stella Technology

Zigron Healthcare

Pittsburgh, PA

13-Jul-16

Compiled by: Morgan Reape Source: Pitchbook

15-Jul-16

Description

Manufacturerer of transformative patient care equipment that allows a nurse to safely ambulate a patient. Provider of a data and technology-based solution. The company collects, manages and reports clinical data and also provides data management, bio-statistics, medical writing and technical services. Developer of rapid quantification technology for viruses. The company provides the tools that deliver biotechnology processes such as vaccine manufacturing, protein expression and antiviral development for vaccine companies, biotechnologies, domestic and foreign government research institutes and universities. Developer of medical devices for the endovascular treatment of neurovascular diseases. The company develops Microbraid technology to create a web aneurysm embolization system for the treatment of both ruptured and unruptured aneurysms. Provider of lupus research, patient education, advocacy, public awareness, lupus research grants and fellowship services. Manufacturer of cancer treatment drugs. The company develops Vipadenant, which is an adenosine receptor antagonist for cancer treatment. Distributor of pharmaceutical products. The company is engaged in the sourcing and distribution of prescription and over-the-counter drugs. Provider of prototyping and product development for biotechnology. The company designs, develops and manufactures products from concept through to production and OEM technologies for automation. Provider of healthcare technology, user experience and product development consulting services. The company provides multi-platform application development (EMR, EHR, PM, Portal), healthcare big data analytics, certification guidance and development (ONC, SureScripts), drug discovery and development, clinical trials, CRM, financial and operational data analytics and new payment models. The company also offers consult on e-prescription, back-end technologies, telehealth and mobile apps for healthcare organizations.

Transaction Value (Millions)

Undisclosed Undisclosed

16.00

380.00

Undisclosed 10.00 16.50 Undisclosed

Undisclosed

23

Monthly Healthcare Review July 2016 Mergers and Acquisitions The following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Acquirer

Target

Zimmer Biomet

LDR Holding

Austin, TX

13-Jul-16

Health Management Company of America McKesson

TK2 Equipment Management HealthQx

Florida

12-Jul-16

Cell Medica

Delenex Therapeutics

Zurich, Switzerland 12-Jul-16

Jazz Pharmaceuticals

Celator Pharmaceuticals

Ewing, NJ

12-Jul-16

Albany Molecular Research Walman Optical

Euticals

Lodi, Italy

11-Jul-16

Eye Care Alliance

Apex, NC

8-Jul-16

Paragon Care

Midas Software Solutions

Port Melbourne, Australia

7-Jul-16

CITIC Capital Partners Erno Laszlo Group London, United Kingdom

7-Jul-16

Merit Medical Systems DFINE

6-Jul-16

Compiled by: Morgan Reape Source: Pitchbook

HQ Location

Date

King of Prussia, PA 12-Jul-16

San Jose, CA

Description

Transaction Value (Millions)

A medical device company focused on designing and commercializing novel and 1100.00 proprietary surgical technologies for the treatment of patients suffering from spine disorders. Distributor of ancillary diagnostic imaging equipment and devices to health care Undisclosed facilities. Developer of data analytics and software services for the healthcare industry. The Undisclosed company offers a payment analytics platform that enables providers, health systems and insurers to operationalize value based reimbursement models. Developer of locally and systemically applied antibody therapeutics. The company’s fragments are being designed for local application by using the benefits of an antibody therapy with only limited systemic exposure. It is developing therapeutic antibody fragments targeting serious medical diseases with high unmet needs. Developer of therapies to treat cancer. The company focuses on CombiPlex, a drug ratio technology platform that enables the development of combination therapies. Developer of pharmaceutical products. The company specializes in custom synthesis and the manufacture of active pharmaceutical ingredients. Retailer of preowned ophthalmic diagnostic instruments. The company sells various devices used in diagnosing eye conditions and also engages in the refurbishment, repair and services of optical technology instrumentation. Provider of software services for diagnostic medical examinations such as ultrasound studies, CT, MRI, echo, holter, ambulatory blood pressure monitoring, spirometry and sleep studies. A merchant wholesaler and distributior of biological and medical products, botanical drugs, herbs, and pharmaceutical products intended for internal and external consumption in such forms as ampoules, tablets, capsules, vials, ointments, powders, solutions, and suspensions. Developer and marketer of radio frequency kyphoplasty products that treat vertebral compression fractures and other spinal disorders in a minamally invasive matter.

Undisclosed

1500.00

358.00 Undisclosed

1.04

Undisclosed

97.50

24

Monthly Healthcare Review July 2016 Mergers and Acquisitions The following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Acquirer

HQ Location

Empyrean Benefit Solutions

Bloom Health

Minneapolis, MN

Ratiolab

SLAMED ING

Frankfurt, Germany 5-Jul-16

VWR International

PAW BioScience Products

Eatontown, NJ

5-Jul-16

Amicus Therapeutics

MiaMed

New York, NY

5-Jul-16

Bristol-Myers Squibb

Cormorant Pharmaceuticals Biotronic NeuroNetwork

Sweden

5-Jul-16

Ann Arbor, MI

5-Jul-16

Provider of neurophysiological intraoperative monitoring services to surgeons and 98.00 healthcare facilities. The company offers real-time remote monitoring through proprietary software and a secure virtual private network.

AFPM Holding

Lausanne, Switzerland Milan, Italy

4-Jul-16

Salzburg, Austria

1-Jul-16

Provider of medical home care equipment for individuals, health professionals and Undisclosed community living. Distributor of life science research products, such as antibodies and diagnostics Undisclosed products. It also provides research and development services. Supplier of medical equipment. The company is an OEM supplier of smart 33.72 consumables for diagnostics, life sciences and medical technology applications.

Brussels, Belgium

1-Jul-16

NuVasive

Bastide Le Confort Medical Bio-Techne Stratec Biomedical

LFB Group

Space Import Export Sony DADC BioSciences Plasma Industries Belgium

Compiled by: Morgan Reape Source: Pitchbook

Date

6-Jul-16

1-Jul-16

Description

Transaction Value (Millions)

Target

Provider of cloud-based technology for healthcare planning that enables employers, employees, and individuals to make health care decisions. It helps employers to determine their spending on health care and employees to find health insurance and health programs on which to spend. Manufacturer and retailer of laboratory instruments including pipettes, manual dispensers, digital burettes, coagulation analyzers, blood cell counters, pulse oximeters and other related products. Manufacturer of sanitary fluid handling products used in the biotechnology, biopharmaceutical and diagnostic industries. The company's primary focus is single-use connectors and components that support the cell culture and purification processes. Developer of brain disorder medicines. The company provides research and development services for cyclin-dependent kinase-like 5 focused on treatment of brain disorders. Developer of therapeutics and related services for cancer and other rare diseases.

Undisclosed

Undisclosed

Undisclosed

89.50

520.00

Producer of plasma derivatives such as coagulation factors, immunoglobulins and Undisclosed albumin.

25

Monthly Healthcare Review July 2016 Mergers and Acquisitions The following table includes mergers and acquisitions for private and public medical devices, biotechnology, pharmaceuticals, and healthcare companies announced over the previous month. Acquirer

Target

HQ Location

Date

Karex

Pasante Healthcare Lancing, United Kingdom

IMCD Group

Mutchler

Harrington Park, NJ 1-Jul-16

Tekadoc

HY Holdings

Phoenix, AZ

Compiled by: Morgan Reape Source: Pitchbook

1-Jul-16

1-Jul-16

Description

Manufacturer of sexual healthcare products. The company provides sexual lubricants, diagnostic kits, disposable gloves, condoms and related products. It also offers cosmetic products including baby care and feminine care products.

Transaction Value (Millions)

8.55

Distributor of specialty chemicals, pharmaceutical and food ingredients. It also Undisclosed provides sourcing, logistics, repacking, sampling, dispensing and testing, and material management services for its products. Provider of healthcare consulting services. The company offers 24-hour access to 156.40 licensed physicians for webcam, telephone and email consultations.

26

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Monthly Healthcare Review July 2016 - BioEnterprise

Monthly Healthcare Review July 2016 IPOs The following table includes the medical devices, biotechnology, pharmaceuticals, and healthcare IPO pricings...

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Monthly Review. Selecciones en castellano
Selecciones en español de la revista estadounidense de economía política Monthly Review. Acceso a las tres etapas bar

depedlucena | July 2016
Jul 1, 2016 - DEPED-SDO LUCENA CITY ADVISORY NO. 28 S 2016 - TEACHERS' DIGNITY COALITION (TDC) LUCENA FORUM RE: MAGNA CA

July 2016 – DepEd Cavite
Description: Addendum to the Notice of Meeting of all ESP Head Teachers and Administrators Download: ... Description: 20

July 2016 - Bristol City Council
days. Works Compounds. Members will recall that they resolved at their last meeting that a report containing proposals f